Catalase antibody

Catalog No. ABIN2717108

This anti-Catalase antibody is a Mouse Monoclonal antibody detecting Catalase in WB, IHC, IF and FACS. Suitable for Human and Monkey.

Quick Overview for Catalase antibody (ABIN2717108)

Target: Catalase (CAT)

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This Catalase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 1B8

Product Details anti-Catalase Antibody

Characteristics: Homo sapiens catalase (CAT)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human CAT (NP_111743) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Catalase

Target: Catalase (CAT)

Alternative Name: CAT

Background: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.

Molecular Weight: 59.6 kDa

Gene ID: 847

NCBI Accession: NM_001752

HGNC: 847

Pathways: Cellular Glucan Metabolic Process, Cell RedoxHomeostasis, Photoperiodism